Muskegon Heights led by as many as 10 points in the second half, then withstood a late Calvary comeback to win the trophy
McBain scored the game-winning basket in the final seconds to end MCC's season.
Troy McManus scored 15 to lead the Norse, who advance to the regional round next week.
Kyle Beebe hit the game-winning shot with two seconds left, part of a 25-point, 13-rebound effort.
Ethan Hill led the Big Reds with 15 points, followed by David Day III and Jordan Briggs both had 14.
The winners of tonight's district championship games advance to next week's regional tournaments
The Eagles, now 24-0, will face Schoolcraft on Tuesday in the D3 state quarterfinals in Edwardsburg
The Tigers, who won despite only scoring two points in the first quarter, captured the first regional title in the history of the program